Stevens-Johnson syndrome. Reasons. Symptoms. Diagnostics. Treatment #002

Antifungal agents: Antiretroviral drugs (e.g. nevirapine, abacavir) and antiviruses (e.g. telaprevir, acyclovir) Anthelmintics and Analgesics (for example, paracetamol) Nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors Antimalarial drugs
The signs and symptoms that occur in the early stages of the disease may be relatively mild. However, this condition usually develops within a few days, so careful monitoring and frequent evaluations are important. In more severe cases, transfer to the burn unit should be considered. Events with late onset of symptoms and more severe illness may be more critical. When admitting such patients, their respiratory status should be especially assessed. One of the potential complications resulting from SCS/TEN is the formation of airway bubbles, upper and lower, ulceration and damage, accompanied by the formation of a crust on the mucous membrane, which can lead to laryngeal stridor, as well as nasopharyngeal congestion and swelling. If there is respiratory distress syndrome, as well as oropharyngeal tissue edema, intubation may be required to maintain respiratory tract function. The determination of arterial blood gases and oxygen saturation will help determine the clinical respiratory status of the patient. Symptoms usually include a sudden rash after the patient has started taking a new medication. There may be watery or macular and smooth atypical lesions, widespread erythema and Nikolsky's sign (the epidermal layer easily peels off when the damaged area is squeezed). Mucosal damage occurs in the form of erosions or ulcers of the eyes, lips, mouth, esophagus, esophagus, gastrointestinal tract, kidneys, liver, anus, genitals, or urethra. Other potential manifestations include fever, swelling of the tongue, diarrhea, vomiting, dysuria, swollen lymph nodes, joint pain, arthritis, bronchitis, shortness of breath, wheezing, hypotension, and dehydration. The patient should be examined as a burn patient, and his or her airway, respiration, and circulation (ABC) should be evaluated. When classifying SCS or TEN, it is important to assess which part of the body surface is damaged, and various methods have been used for this purpose. One of the patient's hands (palms and fingers) makes up about 1% of the total area
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